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• OP Labs formerly Oxford Peptides.
• 150mg/ml | 1500mg/vial
• Store Frozen | Shelf life four months refrigerated
• Sold for research purposes only
• Contact us for Wholesale Orders

Download Product Spec here: L-Glutathione Product Spec.pdf
Please note our in-solution products are made to specification so we do not produce a batch level COA. 

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L-Glutathione

Chemical Name: L-Glutathione
IUPAC Name: (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid
Molecular Formula: C₁₀H₁₇N₃O₆S
Molecular Weight: 307.32 g/mol
CAS Number: 70-18-8
PubChem CID: 124886

Structural Information

SMILES Notation:
C(C(C(=O)N[C@@H](CS)C(=O)NCC(=O)O)N)C(=O)O

InChI:
InChI=1S/C10H17N3O6S/c11-3(1-6(15)16)9(19)13-4(2-7(17)18)5-20-8(12)14/h3-5H,1-2,11H2,(H,12,14)(H,13,19)(H,15,16)(H,17,18)/t3-/m0/s1

InChI Key:
ARZXFDYFZCQDIF-VKHMYHEASA-N

Chirality: L-isomer (specific stereochemistry at two chiral centers: L-glutamate, L-cysteine, and glycine)

Physical and Chemical Properties

• Appearance: White crystalline powder (in raw form); colorless solution
• Solubility: Soluble in water
• pKa Values: α-COOH ~ 2.12, α-NH₃⁺ ~ 9.62, Thiol group ~ 8.75
• Stability: Susceptible to oxidation; commonly stabilized using buffered aqueous solutions in sterile vials for liquid preparations

Common Analytical Identifiers

Identifier Type	Value
ChemSpider ID	111416
UNII	9038-95-3
KEGG Compound	C00051
ChEBI	CHEBI:16856

Spectral Data

• UV Absorbance: Max absorption at ~260 nm (due to peptide bonds)
• NMR Data: Typical for tripeptide structure; distinct shifts from glutamate, cysteine (notably thiol proton), and glycine residues
• Mass Spectrometry (MS):
  [M+H]⁺ = 308.1 m/z (protonated molecule)
  [M−H]⁻ = 306.1 m/z (deprotonated ion in negative mode)

References

1. Meister, A., & Anderson, M. E. (1983). Glutathione. Annual Review of Biochemistry, 52, 711–760. https://doi.org/10.1146/annurev.bi.52.070183.003431
2. Pastore, A., Federici, G., Bertini, E., & Piemonte, F. (2003). Analysis of glutathione: implication in redox and detoxification. Clinica Chimica Acta, 333(1), 19–39. https://doi.org/10.1016/S0009-8981(03)00200-6
3. Wu, G., Fang, Y. Z., Yang, S., Lupton, J. R., & Turner, N. D. (2004). Glutathione metabolism and its implications for health. The Journal of Nutrition, 134(3), 489–492. https://doi.org/10.1093/jn/134.3.489
4. Lu, S. C. (2013). Glutathione synthesis. Biochimica et Biophysica Acta (BBA) – GeneraKeywords: L-Glutathione, Reduced Glutathione, Oxidized Glutathione, GSSG, γ-L-Glutamyl-L-cysteinylglycine, Glutathionum, GSH.