- OP Labs formerly Oxford Peptides.
- Batch HPLC tested at 99%+ purity.
- Store frozen long term or in fridge when ready to be used.
- Sold for research purposes only.
- Contact us for Wholesale Orders.
Download COA here: Thymosin Alpha-1 COA.pdf
Please note if you have a different Batch ID please contact us for the latest COA.
Thymosin Alpha-1 – Technical Information
Peptide Name:
Thymosin Alpha-1 (Tα1)
Synonyms:
Tα1, Thymalfasin, Thymosin α1
Peptide Sequence (Amino Acid):
Ac-Ser–Asp–Ala–Ala–Val–Asp–Thr–Ser–Ser–Glu–Ile–Thr–Thr–Lys–Asp–Leu–Lys–Glu–Lys–Lys–Glu–Val–Val–Glu–Glu–Ala–Glu–Asn–Asp–Lys–Thr–Lys–Lys–Glu
Molecular Formula:
C129H215N33O55
Molecular Weight:
3108.32 g/mol
Length:
28 amino acids
CAS Number:
62304-98-7
PubChem CID:
16132303
IUPAC Name:
N-acetyl-L-seryl-L-aspartyl-L-alanyl-L-alanyl-L-valyl-L-aspartyl-L-threonyl-L-seryl-L-seryl-L-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-aspartyl-L-leucyl-L-lysyl-L-glutamyl-L-lysyl-L-lysyl-L-glutamyl-L-valyl-L-valyl-L-glutamyl-L-glutamyl-L-alanyl-L-glutamyl-L-asparaginyl-L-aspartyl-L-lysyl-L-threonyl-L-lysyl-L-lysyl-L-glutamine
Structure Representation:
SMILES:
CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(O)=O)C(=O)N[C@@H](C(O)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(O)=O)C(=O)N[C@@H](C(O)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(O)=O)C(N)=O
Peptide Classification:
Synthetic 28-amino acid peptide; fragment of prothymosin alpha
Solubility:
Soluble in water, acetic acid, and common aqueous buffers (e.g., PBS)
Storage Guidelines:
– Lyophilized form: store at −20°C
– Reconstituted solutions: store at 2–8°C and use within several days
– Protect from light and avoid repeated freeze-thaw cycles
References
- Garaci, E., Pica, F., Sinibaldi-Vallebona, P., et al. (2007). “Thymosin α1: From bench to bedside.” Annals of the New York Academy of Sciences, 1112(1), 225–234. https://doi.org/10.1196/annals.1415.037
- Goldstein, A. L., Badamchian, M., & Goldstein, A. L. (2004). “Thymosin α1: Biological activities, applications, and implications.” Expert Opinion on Biological Therapy, 4(4), 559–573. https://doi.org/10.1517/14712598.4.4.559
- King, R., Tuthill, C. (2010). “Thymosin alpha 1—A novel therapeutic peptide.” Expert Opinion on Biological Therapy, 10(5), 725–732. https://doi.org/10.1517/14712591003798656
- Romani, L., Bistoni, F., Gaziano, R., et al. (2004). “Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through Toll-like receptor signaling.” Blood, 103(11), 4232–4239. https://doi.org/10.1182/blood-2003-10-3621
Keywords: Thymosin Alpha-1.
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