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Adamax

🔬 Adamax Peptide — Technical Summary

Chemical Identity & Synonyms

• Name: Adamax (also referred to as N‑acetyl Semax–adamantyl)
• Synonyms: Ac‑Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro‑Ala‑Gly‑OH with adamantyl modification; adamantane Semax
• CAS Number: Not assigned / unregistered
• PubChem CID: Not available (synthetic analog)

Amino Acid Sequence & Molecular Data

• Sequence: Ac‑Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro‑Ala‑Gly‑OH with adamantyl appended at C‑terminus ([turn0search0], [turn0search2])
• Molecular Formula: C₂₂H₅₂N₁₆O₆ (reported) :contentReference[oaicite:1]{index=1}
• Molecular Weight: ~1 032.2 Da :contentReference[oaicite:2]{index=2}

Structural Features

• N‑terminal acetylation: Increases resistance to enzymatic degradation :contentReference[oaicite:3]{index=3}
• C‑terminal adamantane moiety: Enhances lipophilicity and stability, adapted from P21 peptide :contentReference[oaicite:4]{index=4}
• Backbone: Derived from neuropeptide Semax (Pro-Gly-Pro) with glycine extension and hydrophobic cap :contentReference[oaicite:5]{index=5}

Physical & Chemical Properties

• Formulation: White lyophilized powder, typically ≥98–99% pure (HPLC-verified) :contentReference[oaicite:6]{index=6}
• Solubility: Often reconstituted in DMSO or aqueous buffer for research use :contentReference[oaicite:7]{index=7}
• Stability & Storage: Stable as powder at 2–8 °C short term; –20 °C long-term :contentReference[oaicite:8]{index=8}

Synthetic Context

• Adamax is a semisynthetic analog of Semax, featuring both N‑acetyl and adamantane modifications to alter pharmacochemical properties :contentReference[oaicite:9]{index=9}

📚 References (Academic/Technical Sources Only)

1. Molecular data and sequence description: “Ac‑Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro‑Ala‑Gly‑OH with adamantyl” from BOC Sciences and MolChanges :contentReference[oaicite:11]{index=11}.
2. Formula C₂₂H₅₂N₁₆O₆ and MW ~1 032.2 Da confirmed by UK‑Peptides and MolChanges :contentReference[oaicite:12]{index=12}.
3. Structural modifications (acetylation and adamantane cap) described by multiple peptide providers (BOC Sciences, MolChanges) :contentReference[oaicite:13]{index=13}.

Keywords: Adamax, adamantane Semax, N‑acetyl Semax‑adamantyl.