- Batch HPLC tested at 99%+ purity.
- Store frozen long term or in fridge when ready to be used.
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Download COA here: Hexarelin COA.pdf
Please note if you have a different Batch ID please contact us for the latest COA.
Hexarelin
Examorelin (INN), also commonly known as hexarelin, is a potent, synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor(GHSR) and a growth hormone secretagogue which was developed by Mediolanum Farmaceutici.[3][4][5][6][7] It is a hexapeptide with the amino acid sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 which was derived from GHRP-6. These GH-releasing peptides have no sequence similarity to ghrelin, but mimic ghrelin by acting as agonists at the ghrelin receptor.[5][6]
References
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Ghigo E, Arvat E, Gianotti L, Imbimbo BP, Lenaerts V, Deghenghi R, Camanni F (March 1994). “Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man”. The Journal of Clinical Endocrinology and Metabolism. 78 (3): 693–698. doi:10.1210/jcem.78.3.8126144. PMID 8126144.
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Imbimbo BP, Mant T, Edwards M, Amin D, Dalton N, Boutignon F, et al. (1994). “Growth hormone-releasing activity of hexarelin in humans. A dose-response study”. European Journal of Clinical Pharmacology. 46 (5): 421–425. doi:10.1007/bf00191904. PMID 7957536. S2CID 19573322.
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Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 617–. ISBN 978-0-412-46630-4.
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Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 117–. ISBN 978-94-011-4439-1.
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Moulin A, Ryan J, Martinez J, Fehrentz JA (September 2007). “Recent developments in ghrelin receptor ligands”. ChemMedChem. 2 (9): 1242–1259. doi:10.1002/cmdc.200700015. PMID 17520591. S2CID 24945528.
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Wang Y, Tomlinson B (March 2009). “Tesamorelin, a human growth hormone releasing factor analogue”. Expert Opinion on Investigational Drugs. 18 (3): 303–310. doi:10.1517/13543780802707658. PMID 19243281. S2CID 71177320.
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Carpino PA (2002). “Recent developments in ghrelin receptor (GHS-R1a) agonists and antagonists”. Expert Opinion on Therapeutic Patents. 12 (11): 1599–1618. doi:10.1517/13543776.12.11.1599. S2CID 83645573.
Keywords: Hexarelin, Examorelin.
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