MOTS-c
MOTS-c 10mg - Image 2
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MOTS-c 10mg

£25.90

In stock

  • OP Labs formerly Oxford Peptides.
  • Batch HPLC tested at 99%+ purity.
  • Store frozen long term or in fridge when ready to be used.
  • Sold for research purposes only.
  • Contact us for Wholesale Orders.

Download COA here: MOTS-c COA.pdf
Please note if you have a different Batch ID please contact us for the latest COA.

MOTS-c – Technical Information

Full Name:
Mitochondrial Open Reading Frame of the 12S rRNA-c (MOTS-c)

Synonyms:
MOTS-c peptide, mitochondrial-derived peptide (MDP), MDP MOTS-c

Molecular Formula:
C₆₂H₉₆N₁₆O₁₃

Molecular Weight:
1394.55 g/mol

Peptide Sequence (Amino Acid):
Met–Arg–Trp–Gln–Glu–Met–Leu–His–Arg–Leu–Leu–Arg–Glu–Lys–Tyr–Arg (MRWQEMLH RLLREK YR)

Length:
16 amino acids

CAS Number:
1334170-40-5

PubChem CID:
Not listed in PubChem due to its nature as a newly discovered mitochondrial peptide

IUPAC Name:
Not commonly listed due to the peptide length and mitochondrial origin; varies by synthesis route

Structure Representation:
SMILES:
Not universally available due to peptide complexity and variation in synthetic forms

Peptide Classification:
Mitochondria-derived peptide (MDP); encoded by an open reading frame within the 12S rRNA of mitochondrial DNA

Solubility:
Water-soluble; typically solubilized in sterile water or PBS (phosphate-buffered saline)

References

  1. Lee, C., Zeng, J., Drew, B. G., et al. (2015). “The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.” Cell Metabolism, 21(3), 443–454. https://doi.org/10.1016/j.cmet.2015.02.009
  2. Kim, K. H., Son, J. M., Benayoun, B. A., Lee, C. (2018). “The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress.” Cell Metabolism, 28(4), 516–524.e7. https://doi.org/10.1016/j.cmet.2018.06.008
  3. Lu, H., Wei, M., Zhai, Y., et al. (2019). “MOTS-c: A novel mitochondrial-derived peptide with emerging roles in human physiology and pathophysiology.” Frontiers in Physiology, 10, 707. https://doi.org/10.3389/fphys.2019.00707
  4. Wang, E., An, J., Yeh, C., et al. (2020). “MOTS-c enhances mitophagy to promote muscle recovery and metabolic health during aging.” Nature Communications, 11, 4262. https://doi.org/10.1038/s41467-020-18082-5

 

Keywords: MOTS-c, MOTSc.

264 reviews for MOTS-c 10mg

  1. Sam Morris –

    No complaints at all.

  2. Esme P. –

    Extremely happy with this.

  3. Georgia Danes –

    Great product and fast shipping.

  4. Richard H. –

    Love everything about it.

  5. Fiona Thomas –

    So glad I bought it.

  6. Gemma-Lee –

    Well worth it.

  7. Ben C. –

    CouldnÕt be better.

  8. Ciara Beckett –

    A must-buy.

  9. Jessica B. –

    ItÕs a perfect fit.

  10. Jade F. –

    High quality.

  11. Antonia A. –

    I love this thing.

  12. Fanni F. –

    Why did this take forever to arrive?

  13. tess w. –

    CouldnÕt be better.

  14. Rhonagh –

    CanÕt stop using it.

  15. Tia B. –

    Fast delivery and excellent product.

  16. Victoria –

    Very versatile.

  17. Gemma Haworth –

    High-quality product.

  18. Ben –

    Truly amazing.

  19. Barb Clifford –

    Lives up to the hype.

  20. Anna C. –

    Fast delivery and works perfectly.

  21. Jade Thompson –

    Great quality product.

  22. Neil Marshall –

    Amazed by the quick delivery.

  23. Emily P. –

    Fantastic performance.

  24. Rebecca A. –

    Totally satisfied with this.

  25. Monique –

    Super happy with how it works.

  26. Kristine –

    Absolutely love using it.

  27. Holly Ward –

    Product came quicker than expected.

  28. Rebecca Lacey –

    Super helpful.

  29. Mark –

    High-quality product.

  30. Frances –

    CanÕt live without it.

  31. Clare M. –

    Disappointed with how long it took to get here.

  32. Matthew –

    Delivery was much slower than expected.

  33. Nicola M. –

    IÕm totally impressed.

  34. Naemi Kumar –

    Delivery was fast and hassle-free.

  35. Emma Mendes da Costa –

    Speedy delivery, couldnÕt be happier.

  36. Naomi P. –

    Super fast delivery, no issues at all.

  37. Vince Chiappinelli –

    ItÕs just fantastic.

  38. Hannah –

    Amazing quality.

  39. Michelle Dunstan –

    This is amazing quality.

  40. Emily –

    Simply amazing.

  41. Lee Cooper –

    Very reliable.

  42. Lisa –

    Happy customer.

  43. Dulcie R. –

    Product arrived fast, love it.

  44. Verified Buyer –

    Best thing IÕve bought.

  45. Edmund N. –

    Truly amazing.

  46. Verified Buyer –

    Does the trick.

  47. Mick –

    Awesome purchase.

  48. Verified Buyer –

    Love this purchase.

  49. Katie R. –

    Absolutely love this.

  50. Richard Mawer –

    Very fast delivery, love the product.

  51. Jo-Ann –

    Delivered much faster than expected.

  52. Will Johnson –

    Product is fine, but the delivery was a joke.

  53. Suzie Irving –

    Exceeded my expectations.

  54. Fraser –

    Absolutely love the quality.

  55. Jarrad Harries –

    Love everything about it.

  56. Claire K. –

    Super quick delivery, very happy.

  57. Rosie Kelly –

    Best quality IÕve had.

  58. Joanne N. –

    Delivered fast, love the product!

  59. Sydney King –

    Fast shipping, just as described.

  60. Ian Bridle –

    Just what I was looking for.

  61. Julie –

    CouldnÕt be happier.

  62. Sarah C. –

    Best purchase ever.

  63. Sophie Harris –

    Top-notch quality.

  64. Troy Miles –

    Happy customer.

  65. Sallyann W. –

    CouldnÕt be more satisfied.

  66. Laura –

    Was expecting faster delivery, very disappointed.

  67. Debbie Edwards –

    Super quick delivery, very happy.

  68. Verified Buyer –

    Very happy with the quality.

  69. Jackie O. –

    CanÕt live without it now.

  70. Georgie Kelly –

    Got here faster than anticipated.

  71. Talia –

    Ridiculously slow delivery.

  72. Kayleigh –

    Arrived so fast, couldnÕt believe it.

  73. susan craker –

    No complaints at all.

  74. Anastacia –

    Great purchase.

  75. Anonymous –

    Very pleased with this.

  76. Suzanne Cruwys –

    Great quality product.

  77. Hannah Veasey –

    Excellent performance.

  78. Alexandra B. –

    Delivery was super quick, love it.

  79. Angelina Perrett –

    Delivered much faster than expected.

  80. Cilia –

    Waited way too long for this.

  81. Maria D. –

    Speedy delivery, couldnÕt be happier.

  82. Emily Kew –

    Beyond my expectations.

  83. Cheraldine W. –

    Shipping took way too long.

  84. Anonymous –

    Extremely slow shipping.

  85. Anonymous –

    Took much longer than expected to arrive.

  86. Anonymous –

    Not impressed with the shipping speed.

  87. Klaudia –

    Definitely wouldnÕt recommend.

  88. Saara Hanso –

    Took way too long to arrive.

  89. Tim D. –

    Was expecting faster delivery, very disappointed.

  90. Mark T. –

    Waited way too long for this.

  91. Elaine Budd –

    Took much longer than expected to arrive.

  92. Jessica Henderson –

    Had to wait ages for this.

  93. Kim –

    Very disappointed with the performance.

  94. Heather –

    Amazing craftsmanship.

  95. Natalie –

    Fast delivery and works great.

  96. Anonymous –

    Fast delivery, exceeded my expectations.

  97. Paula –

    A great product.

  98. Christine Blake –

    IÕm really pleased with this.

  99. Lisa A. –

    Great purchase.

  100. Raakhi Kadambi –

    Impressed by the fast delivery!

  101. Anonymous –

    Delivery was fast and hassle-free.

  102. Gemma V. –

    Worth every penny..

  103. Memphis –

    So pleased with this.

  104. Anonymous –

    Fast delivery and high quality.

  105. David –

    Super happy I found this.

  106. Ashton Leung –

    So glad I found this.

  107. Anonymous –

    Excellent quality product.

  108. Autumn K. –

    Happy customer.

  109. Tony Dove –

    Super helpful.

  110. Steven –

    So pleased with this.

  111. Seema D. –

    A must-buy.

  112. Delme –

    ItÕs a perfect fit.

  113. Sarah –

    Great value.

  114. Anonymous –

    Five stars.

  115. Dan Twine –

    A real gem.

  116. Sandor Elteto –

    I love this thing.

  117. Harley –

    CanÕt recommend enough.

  118. Samantha K. –

    Amazing quality.

  119. Perry Farman –

    Love how it performs.

  120. Sarah Taylor –

    Absolutely love using it.

  121. Melinda –

    Very high-end.

  122. Kyle D. –

    ItÕs really top-notch.

  123. Emily M. –

    Extremely happy with my choice.

  124. Samantha B. –

    Performs better than I thought.

  125. Rachael Anderson –

    Fast delivery, very impressed.

  126. Paolo –

    Fast delivery and excellent product.

  127. Ellen Richardson –

    Got it fast, very pleased with the quality.

  128. Lara H. –

    Got here faster than anticipated.

  129. Rachel –

    Delivery was fast and hassle-free.

  130. Anonymous –

    Very fast delivery, love the product.

  131. Caron Butler –

    Product arrived quickly, just as described.

  132. Charlotte –

    Delivered fast, love the product!

  133. Janet –

    Arrived fast, no complaints at all.

  134. abigail –

    Worth every penny.

  135. Emma A. –

    Awesome quality.

  136. Emma –

    CouldnÕt be happier.

  137. Paul –

    ItÕs awesome.

  138. Mike Eve –

    Totally dependable.

  139. Sophie –

    Performs wonderfully.

  140. Susan Gardler –

    This is an incredible buy.

  141. Bailey –

    Highly recommend.

  142. Paul R. –

    Well worth it.

  143. Claudia Gozzi –

    Super useful.

  144. Laura –

    Love the results.

  145. Karen Yvonne Hills –

    So glad I found this.

  146. Rhoslyn –

    Totally satisfied with this.

  147. Stefanie Camborne-Paynter –

    Fast delivery and perfect product.

  148. Alice B. –

    Arrived so fast, couldnÕt believe it.

  149. Darrell Roberts –

    Arrived fast, amazing product.

  150. Khilna –

    IÕm obsessed.

  151. Gemma –

    Great design and quality.

  152. Paula P. –

    Incredibly useful.

  153. Paula Kenrick –

    ItÕs perfect for me.

  154. Venetia –

    ItÕs awesome.

  155. Sam –

    Super happy with my purchase.

  156. Charlotte –

    A great buy.

  157. Kay Hunt –

    Excellent choice.

  158. Sarah D. –

    A must-buy.

  159. Hannah Horan –

    IÕm blown away by the quality.

  160. Arthur Caulfield –

    Very happy with the quality.

  161. Helen Robinson –

    This is a game-changer.

  162. Jamie –

    Thrilled with this purchase.

  163. Dawn –

    ItÕs perfect for me.

  164. Anonymous –

    The best IÕve seen.

  165. Oliver Anthony –

    Excellent quality.

  166. Adrian P. –

    Beyond impressed.

  167. Natalia –

    So happy with the fast delivery!

  168. Aimee R. –

    Arrived so fast, couldnÕt believe it.

  169. Stacey G. –

    Delivered quickly, very satisfied.

  170. Ashley Berrisford –

    Worth every penny.

  171. Anonymous –

    Great design and quality.

  172. Lewis Bensted –

    CouldnÕt be better.

  173. Joanne Brettle –

    A total game-changer.

  174. Rebecca Barnes –

    Awesome purchase.

  175. Kirsten Hendry –

    Performs better than I thought.

  176. Michelle Cooke –

    The best product IÕve ever used.

  177. Sharon M. –

    CouldnÕt be happier.

  178. Lisa Hoey –

    ItÕs perfect.

  179. susan c. –

    ItÕs a lifesaver.

  180. Danielle H. –

    Loving it so far.

  181. Elizabeth –

    Very reliable.

  182. Fiona W. –

    Best decision ever.

  183. Julia F. –

    Highly satisfied.

  184. Melinda –

    Extremely satisfied.

  185. Toni –

    Just amazing.

  186. Sophie Palmer –

    Fast delivery.

  187. Zoe –

    IÕm super satisfied.

  188. Rachel Rendle –

    Highly reliable.

  189. Lauren P. –

    Great product, highly recommend.

  190. Anna Pawlowska –

    Perfect purchase.

  191. Audrey Holmes –

    No complaints at all.

  192. Nil Wil –

    Delivers as promised.

  193. Viki B. –

    Great addition to my collection.

  194. Stephen –

    Great product, great price.

  195. Michelle –

    Very impressed with the results.

  196. Lisa Allen –

    Works great.

  197. Katie –

    Totally worth it.

  198. Sarah Fisher –

    Super happy with my purchase.

  199. Nicola B. –

    The best product IÕve ever used.

  200. Megan –

    Super quick delivery, love the product.

  201. Melanie –

    Super quick delivery, very happy.

  202. Joe Madren –

    Super speedy shipping, product is excellent.

  203. Wayne Howe –

    Product came quicker than expected.

  204. Tina Appleton –

    Fast delivery, works exactly as described.

  205. Rachel Turner –

    Delivery was super quick, love it.

  206. Miss Kavita Gajjar –

    Just perfect.

  207. Rhiannon Cooper –

    Very versatile.

  208. Matthew McDermott –

    Superb service, very fast delivery, as with most peptides, the effects are not acute, so can’t comment on that, but they are certainly sterile.

    I have ordered multiple times since my first order, which I think says everything?

  209. Rachel Turner wilkinson –

    Fantastic product

  210. Anonymous –

  211. Duane –

    It was easy to use and no adverse effects. It seems to be having a good effect but more time is needed on this to verify its efficacy.

  212. Jack –

    Quick delivery and reasonable price

  213. Anonymous –

    Great for research

  214. Sebastian Schreiber –

  215. Dylan C. –

  216. Elly –

    Fast efficient service and great value

  217. Luke –

    Came via next day delivery and without testing vials from experience quality is good.

  218. Steven Jones –

  219. audrius leliuga –

    Good

  220. Chris S. –

    Fast delivery great product

  221. Jonny –

  222. Stephen Hill –

    Great product, great service….used OP before and never disappointed. First time using MotsC in my peptide stack so I can update with results

  223. richard b. –

    This stuff is real from the first day I used it I felt the energy. It’s very strong

  224. Sean M. –

    Arrived quickly and can feel a difference in energy levels already

  225. Mark France –

    Excellent again

  226. Simon G. –

    I’ve used Oxford Peptides on a number of occasions for different products and been very happy with the quality of each peptide purchased, well priced and quick delivery

  227. paul w. –

  228. Russell H. –

    Perfect quality

  229. Russell –

  230. Jarnail Singh –

  231. david john THOMAS –

  232. Anonymous –

    Excellent product

  233. Anonymous –

  234. Paul Russell –

    Excellent product, very satisfied

  235. Kevin C. –

  236. Anonymous –

    Not been having it long enough yet to coment

  237. Anonymous –

    Came fast as always and is a high quality product, again. Oxford peptides is consistent and reliable.

  238. Ryan C. –

    Ordered a few times from Oxford peptides, never had any issues, good customer service and fast delivery. All the products used work well.

  239. Richard Meynell –

    Still waiting for delivery

    • clickanddrop –

      If there are issues with the order just let us know and we will try to resolve.

  240. Gerhardus Engelbrecht –

    Fast delivery & great quality peptides – have ordered a few times very happy with product

  241. Philip B. –

    Mots c research going well, appears to be good quality and results

  242. Clinton W. –

    great service ,delivered within a couple of days ,to early to say about quality of products but i`m sure they`ll be no problem from reading other reviews .

  243. Shaun –

    More energy just feel better overall

  244. Michelle S. –

    Love

  245. Jarnail singh –

    The product is amazing the strength and quality is 100% bang on

  246. Gary T. –

    Excellent

  247. Gary T. –

    Excellent

  248. Paul Stephenson –

    Awesome

  249. James H. –

  250. Paul Russell –

    Great product .very effective

  251. John Chambers –

    Competitive price,good quality too

  252. Alan W. –

    Ordered over a week ago and still not arrived. Emailed them twice to say it’s not arrived. Spoken with Royal Mail who say I have to get Oxford labs to report it, which I have done twice with no response as yet. Very disappointed as I have had great service from them previously.

    • clickanddrop –

      If we haven’t replied it’s because we haven’t received your email. You will note our overwhelmingly positive feedback on customer service as it is something we take seriously. Please try again using our contact us form.

  253. Connor T. –

    That’s the shiiiiii

  254. Migel –

    excellent quality and value for money.. i will definitely purchase more in the future ,super fast delivery too..

  255. Kelly Meyrick –

    Great peptide

  256. Jonathan P. –

    Great service

  257. David C. –

    Great service and fast delivery as promised evem during christmas period.

  258. Bruce D. –

  259. James B. –

    Great product and fast delivery

  260. Chris P. –

    Great product

  261. Ciaran D. –

    Love it

  262. Richard Dolan –

    Haven’t used yet so no comment

  263. Stuart –

    Great stuff did exactly what you here that it does for you.

  264. Sara garatly –

Only logged in customers who have purchased this product may leave a review.

In stock

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The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

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