- OP Labs formerly Oxford Peptides.
- Batch HPLC tested at 99%+ purity.
- Store frozen long term or in fridge when ready to be used.
- Sold for research purposes only.
- Contact us for Wholesale Orders.
Download COA here: Matrixyl COA.pdf
Please note if you have a different Batch ID please contact us for the latest COA.
Matrixyl (Palmitoyl Pentapeptide-4)
Chemical & Physical Data
| Property | Specification |
|---|---|
| Synonyms / Other Names | Matrixyl; Palmitoyl Pentapeptide-4; PAL-Lys-Thr-Thr-Lys-Ser; Palmitoyl-KTTKS; Palmitoyl Pentapeptide-3 (older name) medkoo.com+2molnova.com+2 |
| CAS Number | 214047-00-4 medkoo.com+2molnova.com+2 |
| Molecular Formula | C₃₉H₇₅N₇O₁₀ targetmol.com+2molnova.com+2 |
| Molecular Weight | ~802.07 Da medkoo.com+2molnova.com+2 |
| Sequence | Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH (a palmitoylated pentapeptide) medkoo.com+2molnova.com+2 |
| Purity | ≥ 98% (HPLC) typical; some batches ≥99% depending on supplier molnova.com+2peptide.shop+2 |
| Form | Lyophilised powder / solid; off-white to white appearance medkoo.com+2ChemicalBook+2 |
| Storage Conditions | Store desiccated, at −20 °C or below; avoid moisture and light molnova.com+2broadpharm.com+2 |
| Solubility | Soluble in DMSO; also solubility in acetic acid or dilute aqueous buffers depending on formulation; water solubility may be limited targetmol.com+2ChemicalBook+2 |
Description
Matrixyl (Palmitoyl Pentapeptide-4) is a synthetic matrikine peptide that consists of a palmitoyl (fatty acid) moiety attached to a short peptide of five amino acids (KTTKS). The palmitoyl modification increases lipophilicity, assisting in interaction with lipid components in formulations and aiding in penetration/affinity in topical systems. targetmol.com+2molnova.com+2
It is commonly used as a cosmetic peptide active ingredient due to its demonstrated ability in in vitro and formulation-testing settings to support synthesis of extracellular matrix (ECM) components, such as collagen and other dermal matrix proteins, and to modulate skin surface texture in cosmetic formulations. matrixylinside.com+2SpecialChem+2
Applications in Research / Formulation
-
For formulation of topical cosmetic or dermal products (e.g. creams, serums, lotions) where peptide acts as an active ingredient in skin-care systems. SpecialChem+1
-
As component in INCI-listed ingredient blends including Matrixyl®, Matrixyl® 3000, etc. matrixylinside.com+1
-
As a model peptide for studies of peptide stability, lipid conjugation effects, extracellular matrix signalling in skin biology research.
-
For testing compatibility with other cosmetic ingredients (emollients, hydrating agents, preservatives).
Handling & Stability
-
Reconstitute from lyophilised powder shortly before use in a solvent appropriate to experimental or formulation system (e.g. DMSO, dilute acid, water or buffer).
-
Aliquot upon reconstitution to avoid repeated freeze-thaw or multiple exposures to moisture/air.
-
Store reconstituted peptide at 4 °C for short-term use; long-term storage should be at −20 °C or lower.
-
Protect from exposure to strong oxidizers, extreme pH, or high temperatures, all of which can degrade peptide or oxidize sensitive residues.
Specifications Summary
| Property | Typical Value |
|---|---|
| Purity | ≥ 98% (HPLC) |
| Appearance | White to off-white lyophilised powder |
| Peptide Length | 5 amino acids + palmitoyl lipid moiety |
| Molecular Weight | ~802.07 Da |
| Storage | −20 °C, desiccated, protected from light |
| CAS | 214047-00-4 |
Chemical Name / IUPAC Style
N-(palmitoyl)-Lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine (palmitoyl-KTTKS) — full peptide with palmitoyl (hexadecanoyl) fatty acid modification at N-terminus. molnova.com+2targetmol.com+2
References
-
MedKoo / MolNova catalog data — basic chemical data including molecular formula, sequence, purity. medkoo.com+1
-
Sinoway Industrial COA — specifications including HPLC purity, appearance, solvent solubility. ChemicalBook
-
Croda / Sederma Matrixyl® information — background on the peptide’s activity in formulation and labelled INCI/functional role. matrixylinside.com+2SpecialChem+2
Keywords: Matrixyl.










Denise Wadey –
Loving these peptides and a great service 🙏
Lukasz B. –
High quality products and super fast delivery
Denise Wadey –
Great service.. would appreciate how much bac water to add